Biologic Treatment of Severe Asthma

Biologic cut steroid dose in severe asthma

Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program.

BACKGROUND Biologic factors are known to contribute to asthma severity. It is unknown whether these factors differentially contribute to asthma severity in black compared with white subjects. OBJECTIVE We sought to assess the extent to which racial disparities between black and white subjects with severe asthma are attributable to physiologic, immunoinflammatory, and sociodemographic variable...

Evaluation of Omeprazole in the Treatment of Moderate to Severe Persistent Asthma in Children

Background and Objective: Asthma is the most common chronic disease of childhood. The disease is caused by a temporary blockage of airflow due to chronic inflammation of the airways . One of the conditions that often occur with asthma and exacerbate disease, is gastroesophageal reflux. The aim of this study is to evaluate the role of acid suppressing therapy in patients with refractory asthma...

Combination biologic therapy for the treatment of severe palmoplantar pustulosis

IL: interleukin INTRODUCTION Psoriasis is a common chronic disease andmay be the most prevalent autoimmune disease. The estimated prevalence is 2% to 4% of the global population. Fortunately, providers have a plethora of medications to choose from, but even so, some cases can be very difficult to treat. Herein, we present a challenging case of palmoplantar pustulosis primarily affecting the sol...

Future biologic therapies in asthma.

Despite the administration of appropriate treatment, a high number of patients with asthma remain uncontrolled. This suggests the need for alternative treatments that are effective, safe and selective for the established asthma phenotypes, especially in patients with uncontrolled severe asthma. The most promising options among the new asthma treatments in development are biological therapies, p...